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I'm a research fellow at Boston Children's Hospital, Harvard University, doing research on the biological role of liquid condensates  using single-molecule biophysics with Prof. Sua Myong

Contact: nilimeshchem@gmail.com

nilimesh.das@childrens.harvard.edu

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Research

Selected Publications
(Publications as first or corresponding author)
^ denotes equal contribution
* denotes corresponding author

No product

 

Tracking heterogenous protein aggregation at nanoscale through fluorescence correlation spectroscopy

Bisal Halder^, Shreya Ghosh^, Tanmoy Khan^, Suvendu Pal^, Nilimesh Das* and Pratik Sen*

Photochem. Photobiol, 2024, early view

 

 

 

 

 

 

 

The Shift of Excitation Spectra at Blue Edge of Emission (BEEmS) as a New Methodology to Probe Heterogeneity

Nilimesh Das, Tanmoy Khan and Pratik Sen*

Chem. Phys., 2024, 577, 112138

 

 

 

 

 

 

 

 

 

 

 

 

 

Associated Water Dynamics Might Be a Key Factor Affecting Protein Stability in the Crowded Milieu

Nilimesh Das, Ejaj Trif, Abhijit Dutta and Pratik Sen*

J. Phys. Chem. B, 2023, 127, 3151-3163

 

 

 

 

 

Viscosity Decoupling does not Guarantee Dynamic Heterogeneity: A Way Out

Nilimesh Das, Navin Subba and Pratik Sen*

J. Photochem. Photobiol. A, 2023, 436, 114361.

 

Site‐specific Heterogeneity of Multi‐domain Human Serum Albumin and its Origin: A Red Edge Excitation Shift Study

Nilimesh Das, Subhrasmita Sahu, Tanmoy Khan and Pratik Sen*

Photochem. Photobiol, 2023, 99, 538-546

Massive Amplification of Photoluminescence and Exceptional Water Stability of MAPbBr3 Nanocrystals through Core-Shell Nanostructure formation in a Self-Defense Mechanism

Shovon Chatterjee, Tanmoy Khan, Arghya Sen, Nilimesh Das* and Pratik Sen*

Mater. Adv., 2022, 3, 7360-7369.

Macromolecular crowding: how shape and interaction affect the structure, function, conformational dynamics and relative domain movement of a multi-domain protein

Nilimesh Das and Pratik Sen*

Phys. Chem. Chem. Phys., 2022, 24, 14242-14256.

 

 

Tracking Wormlike Micelle Formation in Solution: Unique Insight through Fluorescence Correlation Spectroscopic Study

Navin Subba^, Nilimesh Das^ and Pratik Sen*

Langmuir, 2022, 38, 2486-12494.

 

 

Does Microsecond Active-Site Dynamics Primarily control Proteolytic Activity of Bromelain? Clues from a Single Molecular Level Study with a Denaturant, a Stabilizer and a Macromolecular Crowder

Nilimesh Das* Sandeep Yadav, Kuldeep Singh Negi and Pratik Sen*

BBA Advances, 2022, 2, 100041.

A Novel Quinoline Derivative for Selective and Sensitive Visual Detection of PPB Level Cu2+ in Aqueous Solution

Nilimesh Das, Tanmoy Khan, Aritra Das, Vipin Kumar Jain, Joydev Acharya, Md Serajul, Haque Faizi, Joseph Daniel and Pratik Sen

Curr. Anal. Chem., 2022, 18, 196-203.

 

Dynamic Heterogeneity and Viscosity Decoupling: Origin and Analytical Prediction

Nilimesh Das and Pratik Sen*

Phys. Chem. Chem. Phys., 2021, 23, 15749-15757.

 

 

 

 

 

Correlating Bromelain's activity with its structure and active-site dynamics and the medium's physical properties in a hydrated deep eutectic solvent

Nilimesh Das, Tanmoy Khan, Navin Subba and Pratik Sen*

Phys. Chem. Chem. Phys., 2021, 23, 15749-15757.

 

 

 

 

 

 

 

 

Shape-dependent macromolecular crowding on the thermodynamics and microsecond conformational dynamics of protein unfolding revealed at the single-molecule level

Nilimesh Das and Pratik Sen*

J. Phys. Chem. B, 2020, 124, 5858-5871.

Size-dependent macromolecular crowding effect on the thermodynamics of protein unfolding revealed at the single molecular level

Nilimesh Das and Pratik Sen*

Int. J. Biol. Macromol., 2019, 26, 843-854

 

 

 

Sucrose-Induced Stabilization of Domain-II and Overall Human Serum Albumin against Chemical and Thermal Denaturation

Sukanta Shil, Nilimesh Das*, Bhaswati Sengupta, Pratik Sen*

ACS Omega, 2018, 3, 16633-16642

 

 

 

 

Structural, functional, and dynamical responses of a protein in a restricted environment imposed by macromolecular crowding

Nilimesh Das and Pratik Sen*

Biochemistry, 2018, 57, 6078-6089.

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